You can make a difference by participating in a clinical trial. These are some of the many research studies that are being conducted here in Northeast Ohio. If you have questions about a particular study, please refer to the contact information provided with each listing.

• Multiple clinical research trials
      Your Diabetes Endocrine Nutrition Group
  Multiple studies including the only remaining inhaled insulin in development. Participants will be compensated for their time and travel.

• Pregnancy study
      For women planning to become pregnant in the next year.

• LANCET Trial
      Participation and contact information
      Background and Eligibility
  The LANCET trial will investigate whether Lantus, a long-acting insulin injection, either alone or in combination with metformin, is effective in reducing C-reactive protein (CRP) in adults with type 2 diabetes. CRP is a marker of chronic low-level inflammation, a new risk factor for diabetes, heart attack, stroke, and other cardiovascular events.

• Diabetic Eye Disease/Macular Edema
      Treatment of Macular Edema - 4 studies

• Gastric Bypass vs. Medical Therapy - Type 2 Diabetes
      Cleveland Clinic - STAMPEDE study
  This novel study, named STAMPEDE (Surgical Therapy And Medications Potentially Eradicate Diabetes Efficiently) will help define the most effective therapy to treat patients with diabetes and a BMI between 30 – 40 kg/m2. Subjects will be randomized to either advanced medical therapy alone or advanced medical therapy combined with gastric bypass surgery. This study will be enrolling 150 patients. Subjects will be followed at the Cleveland Clinic for 5 years.

• Diabetes Management in Older Adults Study - Type 2 Diabetes
      Myers Research Institute of Menorah Park

• Inhaled Insulin Study - Type 2 Diabetes
      St. Vincent Charity Hospital - INHALE study

• Medication Study - Type 2 Diabetes
      Cleveland Clinic Beachwood Family Health Center

• Heart attack, stroke, or vascular disease and high cholesterol
      St. Vincent Charity's Lipid Research Center - NIH AIM HIGH trial

• Foot Problems - Type 1 Diabetes
      BME Study

• Sleep Apnea
      Effects of Sleep Apnea Treatment on Metabolic Syndrome

• Adolescents – Type 2 Diabetes
      TODAY (Treatment Options for Type 2 Diabetes in Adolescents and Youth)

• Children – Type 2 Diabetes
      TODAY (Treatment Options for Type 2 Diabetes in Adolescents and Youth)

• Diabetes - Gestational
      Diabetes in Pregnancy Study

• Diabetes - Type 2
      TODAY (Treatment Options for Type 2 Diabetes in Adolescents and Youth)

• Diabetes - Type 1 or Type 2
      CRIC (Chronic Renal Insufficiency Cohort Study)

• Kidney Problems - Type 1 or Type 2 Diabetes
      CRIC (Chronic Renal Insufficiency Cohort Study)

• Pregnancy – Gestational Diabetes
      Diabetes in Pregnancy Study

For more information on clinical trials and to find comprehensive listings of northeast Ohio trials that are recruiting patients, visit the NIH Clinical Trials site (search "diabetes, Cleveland" or "diabetes, Akron", etc.) or the CenterWatch site (see Trial Listings/Endocrinology).